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لیست داوران سال 1401

لیست داوران سال 1400

اثر تمرینات ترکیبی هوازی و مقاومتی بر سطوح فعال کنندۀ RNA گیرندۀ استروئیدی بافت چربی و شاخص مقاومت به انسولین در موش‌های سالمند ماده

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I

نویسندگان

گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران

چکیده

هدف از مطالعه حاضر بررسی اثر هشت هفته تمرینات ترکیبی هوازی و مقاومتی بر سطوح SRA بافت چربی و شاخص مقاومت به انسولین در موش‌های سالمند بود. 20 سر رت ماده (28-24 هفته، میانگین وزنی 30/13±20/379 گرم) انتخاب و به شیوه تصادفی در دو گروه تجربی و کنترل (10 سر در هر گروه) تقسیم شدند. موش‌ها در گروه تجربی در هشت هفته تمرینات ترکیبی هوازی و مقاومتی، شش روز در هفته شرکت کردند. تمرینات هوازی شامل دویدن روی تردمیل در شدت کم تا متوسط (60-40 درصد سرعت بیشینه به دست آمده در آزمون دویدن بیشینه)، 60 دقیقه در هر جلسه و بدون شیب تردمیل بود. و تمرینات مقاومتی نیز بالا رفتن از نردبان با شدتی معادل 60-40 درصد از نیروی به دست آمده در آزمون بار بیشینه، 15 تکرار با یک دقیقه تناوب استراحت و 45 دقیقه در هر جلسه تمرینی را شامل می‌شد. اجرای هشت هفته تمرینات ترکیبی هوازی و مقاومتی ضمن افزایش معنی‌دار SRA بافت چربی با کاهشی معنی‌دار در سطوح سرمی انسولین، گلوکز ناشتای خون، شاخص مقاومت به انسولین و وزن بدن در گروه تجربی در مقایسه با گروه کنترل همراه بود. علاوه بر این، اجرای هشت هفته تمرینات ترکیبی هوازی و مقاومتی سبب کاهش معنی‌دار وزن بدن در گروه تجربی در پس آزمون در مقایسه با پیش آزمون گردید.چنین به نظر می‌رسد اجرای اجرای هشت هفته تمرینات ترکیبی هوازی و مقاومتی با وجود افزیش سطوح SRA در بهبود مقاومت به انسولین و ترکیب بدن نقش دارد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effect of Combined Aerobic and Resistance Exercise Training on Steroid Receptor RNA Activator and Insulin Resistance Index in Old Female Rats

نویسندگان [English]

  • hamed rashidi
  • Najmeh Rezaeian

Department of physical education, Bojnourd branch, Islamic Azad University, Bojnourd

چکیده [English]

Aim: Steroid Receptor RNA Activator (SRA) is one of long non-coding RNA (LncRNA) playing a dual role glucose homeostasis and insulin resistance. Purpose of this study was to investigate the effect of eight weeks of combined aerobic and resistance training (ART) on adipose tissue levels of SRA and insulin resistance index (HOMA-IR) in old rats. Twenty old female rat (24-28 weeks old, 379/20±13/30 gr) selected and were randomly divided into experimental and control groups (10 ones in each). The rats in the experimental group participated in eight weeks of ART, six days a week. Aerobic training consisted of running on a treadmill at low to moderate intensity (40-60% of the maximum speed obtained in the maximum running test), 60 minutes per session. Resistance training compromised climbing a ladder at an intensity equal to 40-60% of the force obtained in the maximum load test, 15 repetitions with a one-minute rest interval, and 45 minutes per session. Eight weeks of ART resulted in significant increases in adipose tissue levels of SRA in addition to significant decreases in levels of insulin and fasting blood glucose , HOMA-IR and body weight in the experimental group compared to the control group. Furthermore, eight weeks of ART caused in significant decreases in body weight in post-test compared to pre-test. it seems that eight weeks of combined aerobic and resistance training plays a role in improving insulin resistance and body composition despite of increasing SRA levels.

کلیدواژه‌ها [English]

  • Steroid Receptor RNA Activator (SRA)
  • Combined Aerobic and Resistance Training
  • Insulin Resistance
  • Aging
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سوخت و ساز و فعالیت ورزشی
دوره 13، شماره 2
آذر 1402
صفحه 45-56
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  • تاریخ دریافت: 31 تیر 1402
  • تاریخ بازنگری: 12 آبان 1402
  • تاریخ پذیرش: 01 آذر 1402
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