نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I
نویسندگان
1 پژوهشگر پسادکتری فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه کردستان، سنندج، ایران.
2 دانشیار فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، دانشگاه کردستان
چکیده
مقدمه: پژوهش حاضر با هدف بررسی اثر سطوح سرمی برخی نشانگرهای پیشاگهی اختلال قلب در پاسخ به تعامل یک دوره تمرین هوازی و مصرف عصاره چای سبز در مردان مبتلا به دیابت نوع 2 انجام شد. روش کار: 32 مرد مبتلا به دیابت نوع 2 با میانگین سن 9/10 ± 50 سال، در قالب چهار گروه هشت نفر، 1)چای سبز (GT)، 2)چای سبز+ تمرین هوازی (GT+AT)، 3)دارونما (PL) و 4)دارونما + تمرین هوازی (Pl+AT)، بمدت هشت هفته، پروتکل تمرین هوازی را بمدت 60 دقیقه با شدت 65-55% MHR دویدن بر روی تردمیل انجام دادند و عصاره چای سبز را روزانه به مقدار 800 میلیگرم چای سبز مصرف نمودند. نشانگرهای قلبی شامل GDF-15 و NT-proBNP از طریق خونگیری دو مرحلهای پیش آزمون و پسآزمون ارزیابی گردید. تحلیل یافتهها با استفاده از آزمون انووآ با اندازهگیری مکرر و آزمون تعقیبی بونفرونی انجام شد. یافتهها: یافتهها نشان داد که سطوح سرمی نشانگرهای GDF-15 و NT-proBNP در پس آزمون نسبت به پیش آزمون در هر سه گروه GT، GT+AT و Pl+AT کاهش معناداری داشت (000/0>p) که بیشترین کاهش در گروه GT+AT نسبت به گروههای GT و Pl+AT مشاهده شد (000/0>p). نتایج همچنین نشان داد که شاخص HOMA-IR در هر سه گروه GT، GT+AT و Pl+AT در پسآزمون نسبت به پیشآزمون کاهش معنادار داشت (000/0>p). نتیجه‌گیری: در مجموع میتوان گفت که تمرین هوازی، چای سبز و یا تعامل هر دو باعث کاهش معنادار سطوح بیومارکرهای قلبی میگردد که این با بهبود شاخصهای آنتروپومتریکی و بهبود متابولیسم گلوکز در مردان مبتلا به دیابت نوع 2 همراه بود.
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
Investigating the Effects of Aerobic Exercise and Green Tea Extract Consumption on Serum Levels of Cardiac Disorder Prognostic Markers in Men with Type 2 Diabetes
نویسندگان [English]
- Hadi Golpasandi 1
- Mohammad Rahman Rahimi 2
1 Postdoctoral Researcher in exercise Physiology, Department of exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.
2 Department of Exercise Physiology, University of Kurdistan, Sanandaj, Iran.
چکیده [English]
Introduction: This study aims to explore the impact of aerobic exercise and green tea extract consumption on cardiac prognostic markers in men diagnosed with type 2 diabetes. Methodology: The study involved 32 male participants with type 2 diabetes, aged 50 ± 10.9 years, divided into four groups: 1) green tea (GT), 2) green tea combined with aerobic training (GT+AT), 3) placebo (PL), and 4) placebo combined with aerobic training (PL+AT). Over an 8-week period, the AT protocol was performed for 60 minutes at an intensity of 55-65% of maximum heart rate (MHR) on a treadmill. Green tea extract was consumed at a dosage of 800 mg daily. Serum levels of cardiac markers, including GDF-15 and NT-proBNP, were assessed through blood sampling before and after the intervention. Data were analyzed using ANOVA with repeated measures and Bonferroni's post hoc test. Results: The results indicated a significant decrease in serum levels of GDF-15 and NT-proBNP in the post-test compared to the pre-test in the GT, GT+AT, and PL+AT groups (P<0.001). The greatest decrease was observed in the GT+AT group (P<0.001). Additionally, the HOMA-IR index showed a significant decrease in the post-test compared to the pre-test in the GT, GT+AT, and PL+AT groups (P<0.001). Conclusion: The findings suggest that aerobic exercise, green tea extract, or the combination of both significantly reduces cardiac biomarker levels, which is associated with improved anthropometric measures and glucose metabolism in men with type 2 diabetes.
کلیدواژه‌ها [English]
- cardiac biomarker
- GDF-15
- NT-proBNP
- aerobic training
- epigallocatechin gallate and type 2 diabetes
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