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لیست داوران سال 1401

لیست داوران سال 1400

تاثیر تمرینات ورزشی بر نسبت مویرگ به تار عضلانی در افراد در معرض خطر بالای کاهش چگالی عروق کوچک: مطالعه فراتحلیلی

نوع مقاله : مقاله مروری Released under (CC BY-NC) license I Open Access I

نویسندگان

1 دانشیار فیزیولوژی ورزشی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران

2 استادیار فیزیولوژی ورزشی، دانشکده علوم انسانی، گروه علوم ورزشی، دانشگاه هرمزگان، بندرعباس، ایران

3 دانشیار فیزیولوژی ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران

چکیده

مقدمه: بسیاری از بیماری‌ها سبب کاهش چگالی عروق کوچک در عضلات اسکلتی می‌شوند و تعیین کمّی اندازه اثر تمرینات ورزشی بر نسبت مویرگ به تار عضلانی می‌تواند در دقیق‌سازی نسخه‌های ورزشی ویژه افراد مستعد، کاربردی باشد. هدف مطالعه حاضر تعیین اندازه اثر تمرینات ورزشی بر نسبت مویرگ به تار عضلانی در افراد در معرض کاهش چگالی عروق کوچک بود. روش کار: جستجو برای مقالات انگلیسی در پایگاه­های اطلاعاتی وب آو ساینس، اسکوپوس و پابمد بدون محدود کردن سال انتشار تا فوریه سال 2023 انجام شد. اندازه اثر تفاوت(WMD) با فاصله اطمینان 95 % با استفاده از مدل اثر تصادفی انجام شد. همبستگی بین متغیرها با استفاده از فرارگرسیون مدل اثرات ثابت بررسی شد. یافته‌ها: اندازه اثر کلی مستخرج از 308 آزمودنی مورد شمول در 22 مداخله تمرین ورزشی، برابر با 21/0 (26/0  تا 17/0 95% CI:) به دست آمد (014/0=p، 16/44=I2). طبق نتایج فرارگرسیون مدل اثرات لحظه‌ای بین مقدار تغییرات نسبت مویرگ به تار عضلانی آزمودنی‌های مورد شمول در مداخلات مختلف با سن آنها همبستگی معنی‌داری مشاهده نشد (92/0=p، 00/0=r و 099/0=z). این اندازه اثر در تحقیقات دارای مدت تمرین کمتر از هشت هفته (3=n) برابر با 18/0، در تحقیقات دارای مدت هشت هفته (7=n) برابر با 22/0 و در تحقیقات دارای بیش از هشت هفته (12=n) برابر 22/0 بود (001/0=p، 68/9=Z). همچنین اندازه اثر تمرینات ورزشی HIIT و هوازی شدید (239/0=MD) از اندازه اثر مستخرج برای تمرینات MICT و هوازی (206/0=MD) بیشتر بود (001/0=p، 73/9=Z). نتیجه‌گیری: این یافته‌ها پیشنهاد می‌کنند اثرات تمرین ورزشی بر چگالی عروق عضلات در بیماران مستعد در هر سنی روی می‌دهد و برای افزایش اثرات تمرین حتما باید بر تمرینات طولانی مدت و دارای شدت بالاتر تمرکز شود. بااین‌حال، به دلیل کمبود شواهد همچنان نیاز به بررسی بیشتر باقی است.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effect of Exercise Training on Capillary to Myofiber Ratio in Patients at Higher Risk of Microvascular Rarefaction: A Meta-Analysis Study

نویسندگان [English]

  • Karim Azali Alamdari 1
  • Babak Ebadi Shirmard 2
  • Hadi Rohani 3

1 Associate Professor of Exercise Physiology, Azarbaijan Shahid Madani University, Tabriz, Iran

2 Department of Sport Sciences, Faculty of Humanities, University of Hormozgan, Bandar abbas, Iran

3 Associate Professor, Sport Sciences Research Institute, Tehran, Iran

چکیده [English]

Introduction: Many diseases cause skeletal muscle microvascular rarefaction (MR) and the quantitative determination of the effect size (ES) of exercise training on skeletal muscle capillary to fiber ratio (C/F) can be useful in refining exercise prescriptions for susceptible population. The aim of the present study was to determine the average ES of exercise training on skeletal muscle C/f in patients disposed to MR. Methodology: A search for English articles was conducted in Web of Science, Scopus, and PubMed databases without limiting the year of publication until February 2023. Weighted mean difference (WMD) with 95% confidence intervals was calculated using random effect model. Correlation between variables was investigated using fixed effects model meta-regression. Results: A summary ES achieved as WMD=0.21 (95% CI: 0.17 to 0.26) from the results of 308 subjects, included in 22 exercise training interventions (p=0.014, I2=44.16). No correlations were observed in between the changes in C/F and the age of subjects included in each intervention based on action of the moment’s meta-regression model (r=-0.00, p=0.92, z=0.099). Among the exercise duration categories, interventions less than 8 weeks (n=3) had the least ES on C/F (WMD=0.18), while a WMD of 0.22 were determined for both of interventions with 8 weeks (n=7) and more than 8 weeks duration (n=12) categories (z=9.68, p=0.001). Moreover, interventions in HIIT and intensive aerobic exercise training category had greater ES (WMD=0.23) compared to MICT and aerobic exercise training (WMD= 020) interventions (z=9.73, p=0.001). Conclusions: Taken together, these findings propose that the beneficial effects of exercise training on skeletal muscle microvascular density can ensue in susceptible patients regardless of their age, and higher intensity as well as longer duration exercise programs should be emphasized. however, more investigations remain to be done because of the lack of evidence in this area.

کلیدواژه‌ها [English]

  • Exercise Training
  • Capillary Density
  • Meta-Analysis
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سوخت و ساز و فعالیت ورزشی
دوره 14، شماره 1
اردیبهشت 1403
صفحه 110-132
فایل ها
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  • تاریخ دریافت: 27 آذر 1402
  • تاریخ بازنگری: 18 اسفند 1402
  • تاریخ پذیرش: 19 اسفند 1402
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